Anti-Human SCUBE2 Recombinant Antibody (SAA1911) (HA065013)

Name: Anti-Human SCUBE2 Recombinant Antibody (SAA1911)
Brand: abinScience
SKU: HA065013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HA065013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1911

Objetivo

Signal peptide, CUB and EGF-like domain-containing protein 2, SCUBE2, Protein CEGP1, Scube/You, CEGP1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9NQ36

RRID

Anti-Human SCUBE2 Antibody (SAA1911) (abinScience Cat# HA065013, RRID:AB_3727675)
_x005F_x005F_x000D_

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2) is a ~109 kDa protein. Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane. Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface. Synergizes with DISP1 to increase SHH secretion. Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis.

1. Creanga, A. et al. (2012) Genes & development 26, 1312-25. PMID: 22677548

2. Tukachinsky, H. et al. (2012) Cell reports 2, 308-20. PMID: 22902404

3. Jakobs, P. et al. (2014) Journal of cell science 127, 1726-37. PMID: 24522195

4. Lin, YC. et al. (2017) Arteriosclerosis, thrombosis, and vascular biology 37, 144-155. PMID: 27834687

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human SCUBE2 Antibody (SAA1911)

Referencias

Datasheet

Anti-Human SCUBE2 Recombinant Antibody (SAA1911).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo