

| Numéro de catalogue | HD071014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SEC24C Polyclonal Antibody (HD071014) is a rabbit polyclonal antibody detecting SEC24C. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SEC24C (Asp324-Ser1094). | ||||||||
| Cible | KIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P53992 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5. 1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955 2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046 3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296 4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317 | ||||||||
| Note | For research use only |
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