Anti-Human SENP3 Polyclonal Antibody (HP948014)

Name: Anti-Human SENP3 Polyclonal Antibody
Brand: abinScience
SKU: HP948014
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HP948014

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human SENP3 (Glu311-Val574).

Objetivo

Sentrin-specific protease 3, Sentrin/SUMO-specific protease SENP3, SENP3, SUSP3, SUMO-1-specific protease 3, SSP3

Purificación

Purified by antigen affinity column.

Número de acceso

Q9H4L4

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Sentrin-specific protease 3 (SENP3) is a ~65 kDa protein. Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1.

1. Gong, L. et al. (2006) The Journal of biological chemistry 281, 15869-77. PMID: 16608850

2. Gao, SS. et al. (2020) Science advances 6, eaba7822. PMID: 32832608

3. Zhang, T. et al. (2022) Nature communications 13, 5133. PMID: 36050397

4. Grégoire, S. et al. (2005) Molecular and cellular biology 25, 2273-87. PMID: 15743823

5. Klein, UR. et al. (2009) Molecular biology of the cell 20, 410-8. PMID: 18946085

6. Huang, C. et al. (2009) The EMBO journal 28, 2748-62. PMID: 19680224

7. Yun, C. et al. (2008) The Journal of cell biology 183, 589-95. PMID: 19015314

8. Haindl, M. et al. (2008) EMBO reports 9, 273-9. PMID: 18259216

9. Fanis, P. et al. (2012) Molecular & cellular proteomics : MCP 11, 1263-73. PMID: 22872859

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human SENP3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo