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| カタログ番号 | HP266013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA0222 | ||||
| ターゲット | hSETD3, SETD3, Actin-histidine N-methyltransferase, SET domain-containing protein 3, C14orf154 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q86TU7 | ||||
| RRID | Anti-Human SETD3 IP Antibody (SAA0222) (abinScience Cat# HP266013, RRID:AB_3729756) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Actin-histidine N-methyltransferase (SETD3) is a ~67 kDa protein. Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin. 1. Kwiatkowski, S. et al. (2018) eLife 7. PMID: 30526847 2. Wilkinson, AW. et al. (2019) Nature 565, 372-376. PMID: 30626964 3. Guo, Q. et al. (2019) eLife 8. PMID: 30785395 4. Dai, S. et al. (2019) Nature communications 10, 3541. PMID: 31388018 5. Zheng, Y. et al. (2020) Cell discovery 6, 3. PMID: 31993215 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human SETD3 IP Antibody (SAA0222)
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