Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013)

Name: Anti-Human SETD7 IP Recombinant Antibody (SAA0223)
Brand: abinScience
SKU: HP870013
Price: 126 USD
Availability: InStock

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20ug
50ug
100ug
1mg

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HP870013

Description

Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013) is a mouse monoclonal antibody detecting SETD7 in ELISA, IF, IP. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IF, IP

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA0223

Cible

Lysine N-methyltransferase 7, SET9, SET7/9, Histone H3-K4 methyltransferase SETD7, SET7, SET domain-containing protein 7, SETD7, H3-K4-HMTase SETD7, KIAA1717, Histone-lysine N-methyltransferase SETD7, KMT7

Niveau d'endotoxines

< 10 EU/mg as determined by LAL method.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q8WTS6

RRID

Anti-Human SETD7 IP Antibody (SAA0223) (abinScience Cat# HP870013, RRID:AB_3729757)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Histone-lysine N-methyltransferase SETD7 is a ~40 kDa protein. Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Also has methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins.

1. Wang, H. et al. (2001) Molecular cell 8, 1207-17. PMID: 11779497

2. Nishioka, K. et al. (2002) Genes & development 16, 479-89. PMID: 11850410

3. Xiao, B. et al. (2003) Nature 421, 652-6. PMID: 12540855

4. Martens, JH. et al. (2003) Molecular and cellular biology 23, 1808-16. PMID: 12588998

5. Francis, J. et al. (2005) The Journal of biological chemistry 280, 36244-53. PMID: 16141209

9. Xiao, Y. et al. (2022) Bone research 10, 19. PMID: 35210392

Note

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)

Images

SDS-PAGE

SDS-PAGE for Anti-Human SETD7 IP Antibody (SAA0223).

Reférences

Fiche technique

Anti-Human SETD7 IP Recombinant Antibody (SAA0223).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013)

Aperçu

Images

Reférences

Fiche technique

SDS