中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HP870013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human SETD7 IP Recombinant Antibody (SAA0223) (HP870013) is a mouse monoclonal antibody detecting SETD7 in ELISA, IF, IP. Suitable for Human.
Highlights
|
||||
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA0223 | ||||
| ターゲット | Lysine N-methyltransferase 7, SET9, SET7/9, Histone H3-K4 methyltransferase SETD7, SET7, SET domain-containing protein 7, SETD7, H3-K4-HMTase SETD7, KIAA1717, Histone-lysine N-methyltransferase SETD7, KMT7 | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q8WTS6 | ||||
| RRID | Anti-Human SETD7 IP Antibody (SAA0223) (abinScience Cat# HP870013, RRID:AB_3729757) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Histone-lysine N-methyltransferase SETD7 is a ~40 kDa protein. Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Also has methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. 1. Wang, H. et al. (2001) Molecular cell 8, 1207-17. PMID: 11779497 2. Nishioka, K. et al. (2002) Genes & development 16, 479-89. PMID: 11850410 3. Xiao, B. et al. (2003) Nature 421, 652-6. PMID: 12540855 4. Martens, JH. et al. (2003) Molecular and cellular biology 23, 1808-16. PMID: 12588998 5. Francis, J. et al. (2005) The Journal of biological chemistry 280, 36244-53. PMID: 16141209 9. Xiao, Y. et al. (2022) Bone research 10, 19. PMID: 35210392 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307) |
SDS-PAGE for Anti-Human SETD7 IP Antibody (SAA0223).
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
