

| Numéro de catalogue | HA355014 | ||||||||
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| Description |
Anti-Human SGPP2 Polyclonal Antibody (HA355014) is a rabbit polyclonal antibody detecting SGPP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SGPP2 (Ala2-Tyr87). | ||||||||
| Cible | Sphingosine-1-phosphate phosphatase 2, SPPase2, Spp2, hSPP2, 3.1.3.-, Sphingosine-1-phosphatase 2, SGPP2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8IWX5 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Sphingosine-1-phosphate phosphatase 2 (SGPP2) is a ~44 kDa protein. Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. 1. Ogawa, C. et al. (2003) The Journal of biological chemistry 278, 1268-72. PMID: 12411432 2. Mechtcheriakova, D. et al. (2007) Cellular signalling 19, 748-60. PMID: 17113265 | ||||||||
| Note | For research use only. |
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