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| カタログ番号 | HA355014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SGPP2 Polyclonal Antibody (HA355014) is a rabbit polyclonal antibody detecting SGPP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SGPP2 (Ala2-Tyr87). | ||||||||
| ターゲット | Sphingosine-1-phosphate phosphatase 2, SPPase2, Spp2, hSPP2, 3.1.3.-, Sphingosine-1-phosphatase 2, SGPP2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8IWX5 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sphingosine-1-phosphate phosphatase 2 (SGPP2) is a ~44 kDa protein. Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. 1. Ogawa, C. et al. (2003) The Journal of biological chemistry 278, 1268-72. PMID: 12411432 2. Mechtcheriakova, D. et al. (2007) Cellular signalling 19, 748-60. PMID: 17113265 | ||||||||
| 注意事項 | For research use only. |
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