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Anti-Human SH2D1A Monoclonal Antibody (1A650) (HF717015)

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Anti-Human SH2D1A Monoclonal Antibody (1A650)
Anti-Human SH2D1A Monoclonal Antibody (1A650)
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Vista general
Número de catálogoHF717015
Descripción
Anti-Human SH2D1A Monoclonal Antibody (1A650) [1A650] (HF717015) is a mouse monoclonal antibody detecting SH2D1A in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG
ID de clon1A650
Inmunógeno E. coli - derived recombinant human SH2D1A (Asp2-Pro97).
Objetivo SH2 domain-containing protein 1A, Duncan disease SH2-protein, Signaling lymphocytic activation molecule-associated protein, SLAM-associated protein, T-cell signal transduction molecule SAP, SH2D1A
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O60880
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

SH2 domain-containing protein 1A (SH2D1A) is a ~14 kDa protein. Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2. However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1. Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions.

1. Howie, D. et al. (2002) Blood 99, 957-65. PMID: 11806999
2. Li, C. et al. (2003) The Journal of biological chemistry 278, 3852-9. PMID: 12458214
Nota For research use only.
Imágenes
  • Anti-Human SH2D1A Monoclonal Antibody (1A650)

    SDS-PAGE

    SDS-PAGE for Anti-Human SH2D1A Monoclonal Antibody (1A650)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SH2D1A Monoclonal Antibody (1A650)

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