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Anti-Human SH3PXD2A Polyclonal Antibody (HP455014)

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Aperçu
Numéro de catalogueHP455014
Description
Anti-Human SH3PXD2A Polyclonal Antibody (HP455014) is a rabbit polyclonal antibody detecting SH3PXD2A in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human SH3PXD2A (Met1-Asn129).
Cible KIAA0418, Tyrosine kinase substrate with five SH3 domains, TKS5, SH3 multiple domains protein 1, SH3PXD2A, SH3MD1, SH3 and PX domain-containing protein 2A, Five SH3 domain-containing protein, Adapter protein TKS5, FISH
Purification Purified by antigen affinity column.
Numéro d'accès Q5TCZ1
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

SH3 and PX domain-containing protein 2A (SH3PXD2A) is a ~125 kDa protein. Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

1. Jacob, A. et al. (2016) Journal of cell science 129, 4341-4353. PMID: 27789576
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SH3PXD2A Polyclonal Antibody

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