Anti-Human Siglec-8 Recombinant Antibody (SAA0177) (HP983107)

Name: Anti-Human Siglec-8 Recombinant Antibody (SAA0177)
Brand: abinScience
SKU: HP983107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HP983107
Reactividad de especies	Human
Aplicaciones	FCM, WB
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	SAA0177
Objetivo	SAF2, Sialoadhesin family member 2, SAF-2, Siglec-8, SIGLEC8, Sialic acid-binding Ig-like lectin 8
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q9NYZ4
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Sialic acid-binding Ig-like lectin 8 (SIGLEC8/SAF-2) is a ~54 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. 1. Floyd, H. et al. (2000) The Journal of biological chemistry 275, 861-6. PMID: 10625619 2. Kikly, KK. et al. (2000) The Journal of allergy and clinical immunology 105, 1093-100. PMID: 10856141 3. Pröpster, JM. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E4170-9. PMID: 27357658
Nota	For research use only.

Imágenes

Bioactivity

SEC-HPLC detection for Anti-Human SIGLEC8/SAF-2 Antibody (ABS1401).
Western blot

Western blot analysis was performed using anti-SIGLEC8/SAF-2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human SIGLEC8/SAF-2 (Catalog No: HP983011)
Lane 2: negative control