Anti-Human Siglec-8 Recombinant Antibody (SAA0177) (HP983107)

Name: Anti-Human Siglec-8 Recombinant Antibody (SAA0177)
Brand: abinScience
SKU: HP983107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HP983107
Reactivité des espèces	Human
Applications	FCM, WB
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	SAA0177
Cible	SAF2, Sialoadhesin family member 2, SAF-2, Siglec-8, SIGLEC8, Sialic acid-binding Ig-like lectin 8
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9NYZ4
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Sialic acid-binding Ig-like lectin 8 (SIGLEC8/SAF-2) is a ~54 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. 1. Floyd, H. et al. (2000) The Journal of biological chemistry 275, 861-6. PMID: 10625619 2. Kikly, KK. et al. (2000) The Journal of allergy and clinical immunology 105, 1093-100. PMID: 10856141 3. Pröpster, JM. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E4170-9. PMID: 27357658
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-Human SIGLEC8/SAF-2 Antibody (ABS1401).
Western blot

Western blot analysis was performed using anti-SIGLEC8/SAF-2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human SIGLEC8/SAF-2 (Catalog No: HP983011)
Lane 2: negative control