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Anti-Human Siglec-8 Recombinant Antibody (SAA0177)
Anti-Human Siglec-8 Recombinant Antibody (SAA0177)
Anti-Human Siglec-8 Recombinant Antibody (SAA0177)
Anti-Human Siglec-8 Recombinant Antibody (SAA0177)
Цена(USD):
Спецификация:
  • 50ug
  • 100ug
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHP983107
Реактивность видовHuman
ПримененияFCM, WB
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1, kappa
ID клонаSAA0177
Цель SAF2, Sialoadhesin family member 2, SAF-2, Siglec-8, SIGLEC8, Sialic acid-binding Ig-like lectin 8
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q9NYZ4
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Sialic acid-binding Ig-like lectin 8 (SIGLEC8/SAF-2) is a ~54 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose.

1. Floyd, H. et al. (2000) The Journal of biological chemistry 275, 861-6. PMID: 10625619
2. Kikly, KK. et al. (2000) The Journal of allergy and clinical immunology 105, 1093-100. PMID: 10856141
3. Pröpster, JM. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E4170-9. PMID: 27357658
Примечание For research use only.
Изображения
  • Anti-Human Siglec-8 Recombinant Antibody (SAA0177)

    Bioactivity

    SEC-HPLC detection for Anti-Human SIGLEC8/SAF-2 Antibody (ABS1401).

  • Anti-Human Siglec-8 Recombinant Antibody (SAA0177)

    Western blot

    Western blot analysis was performed using anti-SIGLEC8/SAF-2 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human SIGLEC8/SAF-2 (Catalog No: HP983011)
    Lane 2: negative control

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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