Anti-Human SIX1 Polyclonal Antibody (HA515014)

Name: Anti-Human SIX1 Polyclonal Antibody
Brand: abinScience
SKU: HA515014
Price: 96 USD
Availability: InStock

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Especificación:

20ug
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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HA515014

Descripción

Anti-Human SIX1 Polyclonal Antibody (HA515014) is a rabbit polyclonal antibody detecting SIX1 in ELISA, IHC, WB. Suitable for Mus musculus, Danio rerio, Human, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human SIX1 (Met1-Lys199).

Objetivo

SIX1

Purificación

Purified by antigen affinity column.

Número de acceso

Q15475

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Nombres alternativos

Homeobox protein SIX1, Sine oculis homeobox homolog 1, SIX1

Fondo

Homeobox protein SIX1 is a ~32 kDa protein. Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as a transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2.

1. Ruf, RG. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 8090-5. PMID: 15141091

2. Patrick, AN. et al. (2009) The Journal of biological chemistry 284, 20781-90. PMID: 19497856

3. Patrick, AN. et al. (2013) Nature structural & molecular biology 20, 447-53. PMID: 23435380

4. Brunmeir, R. et al. (2016) PLoS genetics 12, e1006474. PMID: 27923061

5. Coletta, RD. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 6478-83. PMID: 15123840

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-SIX1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse skeletal muscle lysate

Referencias

Datasheet

Anti-Human SIX1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo