Anti-Human SIX1 Polyclonal Antibody (HA515014)

Name: Anti-Human SIX1 Polyclonal Antibody
Brand: abinScience
SKU: HA515014
Price: 96 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA515014

Description

Anti-Human SIX1 Polyclonal Antibody (HA515014) is a rabbit polyclonal antibody detecting SIX1 in ELISA, IHC, WB. Suitable for Mus musculus, Danio rerio, Human, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SIX1 (Met1-Lys199).

Cible

SIX1

Purification

Purified by antigen affinity column.

Numéro d'accès

Q15475

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Noms alternatifs

Homeobox protein SIX1, Sine oculis homeobox homolog 1, SIX1

Contexte

Homeobox protein SIX1 is a ~32 kDa protein. Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as a transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2.

1. Ruf, RG. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 8090-5. PMID: 15141091

2. Patrick, AN. et al. (2009) The Journal of biological chemistry 284, 20781-90. PMID: 19497856

3. Patrick, AN. et al. (2013) Nature structural & molecular biology 20, 447-53. PMID: 23435380

4. Brunmeir, R. et al. (2016) PLoS genetics 12, e1006474. PMID: 27923061

5. Coletta, RD. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 6478-83. PMID: 15123840

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-SIX1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse skeletal muscle lysate

Reférences

Fiche technique

Anti-Human SIX1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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