Anti-Human SLC10A2 Polyclonal Antibody (HC032014)

Name: Anti-Human SLC10A2 Polyclonal Antibody
Brand: abinScience
SKU: HC032014
Price: 96 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HC032014

Description

Anti-Human SLC10A2 Polyclonal Antibody (HC032014) is a rabbit polyclonal antibody detecting ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human SLC10A2 (Asn2-Asn28&Gly104-Ser126&Arg246-Asn284&Gly306-Lys348).

Cible

Ileal sodium/bile acid cotransporter; Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q12908

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Ileal sodium/bile acid cotransporter (SLC10A2) is a ~37 kDa protein. Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation.

1. Wong, MH. et al. (1995) The Journal of biological chemistry 270, 27228-34. PMID: 7592981

2. Craddock, AL. et al. (1998) The American journal of physiology 274, G157-69. PMID: 9458785

3. Weinman, SA. et al. (1998) The Journal of biological chemistry 273, 34691-5. PMID: 9856990

4. Kunst, RF. et al. (2021) Hepatology (Baltimore, Md.) 73, 2577-2585. PMID: 33222321

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human SLC10A2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human SLC10A2 Polyclonal Antibody (HC032014)

Aperçu

Images

Reférences

Fiche technique

SDS