

| Каталожный номер | HC032014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SLC10A2 Polyclonal Antibody (HC032014) is a rabbit polyclonal antibody detecting ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human SLC10A2 (Asn2-Asn28&Gly104-Ser126&Arg246-Asn284&Gly306-Lys348). | ||||||||
| Цель | Ileal sodium/bile acid cotransporter; Apical sodium-dependent bile acid transporter; ASBT; Ileal Na(+)/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na(+)-dependent ileal bile acid transporter; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2; SLC10A2; ASBT; ISBT; NTCP2 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q12908 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ileal sodium/bile acid cotransporter (SLC10A2) is a ~37 kDa protein. Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. 1. Wong, MH. et al. (1995) The Journal of biological chemistry 270, 27228-34. PMID: 7592981 2. Craddock, AL. et al. (1998) The American journal of physiology 274, G157-69. PMID: 9458785 3. Weinman, SA. et al. (1998) The Journal of biological chemistry 273, 34691-5. PMID: 9856990 4. Kunst, RF. et al. (2021) Hepatology (Baltimore, Md.) 73, 2577-2585. PMID: 33222321 | ||||||||
| Примечание | For research use only |
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