

| Numéro de catalogue | HX014014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SLC12A2 Polyclonal Antibody (HX014014) is a rabbit polyclonal antibody detecting SLC12A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SLC12A2 (Asn1002-Ser1212). | ||||||||
| Cible | Solute carrier family 12 member 2, Basolateral Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, SLC12A2, NKCC1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P55011 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Solute carrier family 12 member 2 (SLC12A2/NKCC1) is a ~131 kDa protein. Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume. 1. Vitari, AC. et al. (2006) The Biochemical journal 397, 223-31. PMID: 16669787 2. Yang, X. et al. (2020) Nature communications 11, 1016. PMID: 32081947 3. Mutai, H. et al. (2020) PLoS genetics 16, e1008643. PMID: 32294086 4. Zhang, S. et al. (2021) Communications biology 4, 226. PMID: 33597714 5. Zhao, Y. et al. (2022) Nature communications 13, 2747. PMID: 35585053 6. Neumann, C. et al. (2022) The EMBO journal 41, e110169. PMID: 36239040 7. Moseng, MA. et al. (2022) Science advances 8, eabq0952. PMID: 36306358 8. Payne, JA. et al. (1995) The Journal of biological chemistry 270, 17977-85. PMID: 7629105 | ||||||||
| Note | For research use only. |
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