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| カタログ番号 | HA819014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLC15A2 Polyclonal Antibody (HA819014) is a rabbit polyclonal antibody detecting kidney isoform; Peptide transporter 2; SLC15A2; PEPT2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC15A2 (Asn402-Gln611). | ||||||||
| ターゲット | Solute carrier family 15 member 2; Kidney H(+)/peptide cotransporter; Oligopeptide transporter, kidney isoform; Peptide transporter 2; SLC15A2; PEPT2 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16348 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Solute carrier family 15 member 2 (SLC15A2) is a ~81 kDa protein. Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1. In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate. Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs. Transports the dipeptide-like aminopeptidase inhibitor bestatin. 1. Li, M. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 547-55. PMID: 16434549 2. Sala-Rabanal, M. et al. (2008) American journal of physiology. Renal physiology 294, F1422-32. PMID: 18367661 3. Liu, W. et al. (1995) Biochimica et biophysica acta 1235, 461-6. PMID: 7756356 4. Oppermann, H. et al. (2019) Amino acids 51, 999-1008. PMID: 31073693 5. Charrière, GM. et al. (2010) The Journal of biological chemistry 285, 20147-54. PMID: 20406817 | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-SLC15A2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
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