Anti-Human SLC15A4 Recombinant Antibody (SAA2355) (HC091013)

Name: Anti-Human SLC15A4 Recombinant Antibody (SAA2355)
Brand: abinScience
SKU: HC091013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HC091013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG

ID de clone

SAA2355

Cible

Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1, SLC15A4, PHT1, PTR4

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q8N697

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Solute carrier family 15 member 4 (SLC15A4) is a ~62 kDa protein. Proton-coupled amino-acid transporter that mediates the transmembrane transport of L-histidine and some di- and tripeptides from inside the lysosome to the cytosol, and plays a key role in innate immune response. Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position. Able to transport a variety of di- and tripeptides, including carnosine and some peptidoglycans. Transporter activity is pH-dependent and maximized in the acidic lysosomal environment. Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand, and L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (tri-DAP), the NOD1 ligand.

1. Bhardwaj, RK. et al. (2006) European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 27, 533-42. PMID: 16289537

2. Kobayashi, T. et al. (2014) Immunity 41, 375-388. PMID: 25238095

3. Song, F. et al. (2018) Molecular pharmaceutics 15, 385-393. PMID: 29224352

4. Zhang, Z. et al. (2025) Structure (London, England : 1993) 33, 330-337.e4. PMID: 39719710

5. Oppermann, H. et al. (2019) Amino acids 51, 999-1008. PMID: 31073693

6. Heinz, LX. et al. (2020) Nature 581, 316-322. PMID: 32433612

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Human SLC15A4 Antibody (SAA2355)

Reférences

Fiche technique

Anti-Human SLC15A4 Recombinant Antibody (SAA2355).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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