Anti-Human SLC1A5 Polyclonal Antibody (HS734014)

Name: Anti-Human SLC1A5 Polyclonal Antibody
Brand: abinScience
SKU: HS734014
Price: 168 USD
Availability: InStock

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50ug
100ug

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SDS

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Número de catálogo

HS734014

Descripción

Anti-Human SLC1A5 Polyclonal Antibody (HS734014) is a rabbit polyclonal antibody detecting SLC1A5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human SLC1A5 (Gln154-Asn230).

Objetivo

Baboon M7 virus receptor, SLC1A5, Solute carrier family 1 member 5, ASCT2, RDR, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, ATB(0), Neutral amino acid transporter B(0), M7V1, RDRC

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by antigen affinity column.

Número de acceso

Q15758

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Neutral amino acid transporter B(0) (SLC1A5) is a ~56 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. The preferred substrate is the essential amino acid L-glutamine, a precursor for biosynthesis of proteins, nucleotides and amine sugars as well as an alternative fuel for mitochondrial oxidative phosphorylation. Exchanges L-glutamine with other neutral amino acids such as L-serine, L-threonine and L-asparagine in a bidirectional way. Provides L-glutamine to proliferating stem and activated cells driving the metabolic switch toward cell differentiation.

1. Dun, Y. et al. (2007) Experimental eye research 84, 191-9. PMID: 17094966

2. Pingitore, P. et al. (2013) Biochimica et biophysica acta 1828, 2238-46. PMID: 23756778

3. Scalise, M. et al. (2015) FEBS letters 589, 3617-23. PMID: 26492990

4. Garaeva, AA. et al. (2018) Nature structural & molecular biology 25, 515-521. PMID: 29872227

5. Mazza, T. et al. (2021) FEBS letters 595, 3030-3041. PMID: 34741534

6. Kekuda, R. et al. (1996) The Journal of biological chemistry 271, 18657-61. PMID: 8702519

7. Borowska, AM. et al. (2024) Nature communications 15, 6570. PMID: 39095408

8. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177

9. Oburoglu, L. et al. (2014) Cell stem cell 15, 169-84. PMID: 24953180

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human SLC1A5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human SLC1A5 Polyclonal Antibody (HS734014)

Vista general

Imágenes

Referencias

Datasheet

SDS