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Anti-Human SLC26A8 Polyclonal Antibody (HV071014)

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Aperçu
Numéro de catalogueHV071014
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human SLC26A8 (Thr664-Val970).
Cible Solute carrier family 26 member 8, SLC26A8, Testis anion transporter 1, TAT1, Anion exchange transporter
Purification Purified by antigen affinity column.
Numéro d'accès Q96RN1
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Testis anion transporter 1 (SLC26A8) is a ~109 kDa protein. Antiporter that mediates the exchange of sulfate and oxalate against chloride ions across a membrane. Stimulates anion transport activity of CFTR. May cooperate with CFTR in the regulation of chloride and bicarbonate ions fluxes required for activation of the ADCY10/PKA pathway during sperm motility and sperm capacitation. May play a role in sperm tail differentiation and motility and hence male fertility.

1. Toure, A. et al. (2001) The Journal of biological chemistry 276, 20309-15. PMID: 11278976
2. Lohi, H. et al. (2002) The Journal of biological chemistry 277, 14246-54. PMID: 11834742
3. Rode, B. et al. (2012) Human molecular genetics 21, 1287-98. PMID: 22121115
4. Dirami, T. et al. (2013) American journal of human genetics 92, 760-6. PMID: 23582645
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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