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| カタログ番号 | HA253013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1893 | ||||
| ターゲット | Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Solute carrier family 29 member 1, SLC29A1, Nucleoside transporter, es-type, Equilibrative NBMPR-sensitive nucleoside transporter, ENT1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q99808 | ||||
| RRID | Anti-Human SLC29A1/hENT1 Antibody (SAA1893) (abinScience Cat# HA253013, RRID:AB_3727657) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Equilibrative nucleoside transporter 1 (SLC29A1/hENT1) is a ~50 kDa protein. Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier. 1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669 2. Lum, PY. et al. (2000) Cancer chemotherapy and pharmacology 45, 273-8. PMID: 10755314 3. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552 4. Endres, CJ. et al. (2004) The Biochemical journal 380, 131-7. PMID: 14759222 5. SenGupta, DJ. et al. (2004) Biochemical pharmacology 67, 453-8. PMID: 15037197 6. Visser, F. et al. (2007) The Journal of biological chemistry 282, 14148-57. PMID: 17379602 7. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683 8. Aseervatham, J. et al. (2015) PloS one 10, e0136779. PMID: 26406980 9. Huang, W. et al. (2017) Protein & cell 8, 284-295. PMID: 27995448 10. Niemann, B. et al. (2022) Nature 609, 361-368. PMID: 35790189 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human SLC29A1/hENT1 Antibody (SAA1893)
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