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| カタログ番号 | HC050014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLC2A2 Polyclonal Antibody (HC050014) is a rabbit polyclonal antibody detecting liver; GLUT-2; SLC2A2; GLUT2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC2A2 (Asn32-Ser98&Lys483-Val524). | ||||||||
| ターゲット | Solute carrier family 2, facilitated glucose transporter member 2; Glucose transporter type 2, liver; GLUT-2; SLC2A2; GLUT2 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11168 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2) is a ~57 kDa protein. Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of beta cells. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate and urate. 1. Manolescu, A. et al. (2005) The Journal of biological chemistry 280, 42978-83. PMID: 16186102 2. Corpe, CP. et al. (2013) The Journal of biological chemistry 288, 9092-101. PMID: 23396969 3. Ebert, K. et al. (2017) The Journal of membrane biology 250, 171-182. PMID: 28083649 4. Mueckler, M. et al. (1994) The Journal of biological chemistry 269, 17765-7. PMID: 8027028 5. Colville, CA. et al. (1993) The Biochemical journal 290 ( Pt 3), 701-6. PMID: 8457197 6. Fukumoto, H. et al. (1988) Proceedings of the National Academy of Sciences of the United States of America 85, 5434-8. PMID: 3399500 7. Toyoda, Y. et al. (2025) The Journal of biological chemistry 301, 108485. PMID: 40209957 | ||||||||
| 注意事項 | For research use only |
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