

| Numéro de catalogue | HP576014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SLC30A6 Polyclonal Antibody (HP576014) is a rabbit polyclonal antibody detecting SLC30A6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SLC30A6 (Ser247-Asp334). | ||||||||
| Cible | ZnT-6, Solute carrier family 30 member 6, Zinc transporter 6, ZNT6, SLC30A6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6NXT4 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Zinc transporter 6 (SLC30A6) is a ~51 kDa protein. Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis. 1. Suzuki, T. et al. (2005) The Journal of biological chemistry 280, 30956-62. PMID: 15994300 2. Ohana, E. et al. (2009) The Journal of biological chemistry 284, 17677-86. PMID: 19366695 3. Fukunaka, A. et al. (2009) The Journal of biological chemistry 284, 30798-806. PMID: 19759014 4. Wagatsuma, T. et al. (2022) The Journal of biological chemistry 298, 102011. PMID: 35525268 | ||||||||
| Note | For research use only. |
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