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| カタログ番号 | HP576014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLC30A6 Polyclonal Antibody (HP576014) is a rabbit polyclonal antibody detecting SLC30A6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLC30A6 (Ser247-Asp334). | ||||||||
| ターゲット | ZnT-6, Solute carrier family 30 member 6, Zinc transporter 6, ZNT6, SLC30A6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q6NXT4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc transporter 6 (SLC30A6) is a ~51 kDa protein. Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis. 1. Suzuki, T. et al. (2005) The Journal of biological chemistry 280, 30956-62. PMID: 15994300 2. Ohana, E. et al. (2009) The Journal of biological chemistry 284, 17677-86. PMID: 19366695 3. Fukunaka, A. et al. (2009) The Journal of biological chemistry 284, 30798-806. PMID: 19759014 4. Wagatsuma, T. et al. (2022) The Journal of biological chemistry 298, 102011. PMID: 35525268 | ||||||||
| 注意事項 | For research use only. |
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