Anti-Human SLC31A1 Polyclonal Antibody (HC035014)

Name: Anti-Human SLC31A1 Polyclonal Antibody
Brand: abinScience
SKU: HC035014
Price: 168 USD
Availability: InStock

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Número de catálogo

HC035014

Descripción

Anti-Human SLC31A1 Polyclonal Antibody (HC035014) is a rabbit polyclonal antibody detecting High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; Truncated CTR1 form; SLC31A1; COPT1; CTR1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human SLC31A1 (Asp2-Leu61&Tyr83-His132).

Objetivo

High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; Truncated CTR1 form; SLC31A1; COPT1; CTR1

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

O15431

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

High affinity copper uptake protein 1 (SLC31A1) is a ~21 kDa protein. Uniporter that mediates the transport of copper(1+) from the extracellular space to the cytoplasm, across the plasma membrane and delivers directly copper(1+) to specific chaperone such as ATOX1, via a copper(1+)- mediated transient interaction between the C-terminal domain and a copper(1+) chaperone, thus controlling intracellular copper(1+) levels. May function in copper(1+) import from the apical membrane thus may drive intestinal copper absorption. The copper(1+) transport mechanism is sodium-independent, saturable and of high-affinity. Also mediates the uptake of silver(1+). May function in the influx of the platinum-containing chemotherapeutic agents.

1. Lee, J. et al. (2002) The Journal of biological chemistry 277, 4380-7. PMID: 11734551

2. Eisses, JF. et al. (2005) The Journal of biological chemistry 280, 37159-68. PMID: 16135512

3. Maryon, EB. et al. (2007) The Journal of biological chemistry 282, 20376-87. PMID: 17525160

4. Molloy, SA. et al. (2009) The Journal of biological chemistry 284, 29704-13. PMID: 19740744

5. Larson, CA. et al. (2010) Biochemical pharmacology 80, 448-54. PMID: 20451502

6. Bertinato, J. et al. (2010) Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 24, 178-84. PMID: 20569931

7. Maryon, EB. et al. (2013) The Journal of biological chemistry 288, 18035-46. PMID: 23658018

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human SLC31A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human SLC31A1 Polyclonal Antibody (HC035014)

Vista general

Imágenes

Referencias

Datasheet

SDS