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Anti-Human SLC35B1 Recombinant Antibody (SAA2353) (HC089013)

Anti-Human SLC35B1 Recombinant Antibody (SAA2353)
Anti-Human SLC35B1 Recombinant Antibody (SAA2353)
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  • 1mg
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Aperçu
Numéro de catalogueHC089013
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG
ID de cloneSAA2353
Cible Solute carrier family 35 member B1, ATP/ADP exchanger ER, AXER, Endoplasmic reticulum ATP/ADP translocase, UDP-galactose transporter-related protein 1, UGTrel1, SLC35B1, UGTREL1
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P78383
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Solute carrier family 35 member B1 (SLC35B1) is a ~35 kDa protein. ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane. Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction. Regulates ER energy metabolism and protein biogenesis. Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply. Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER.

1. Klein, MC. et al. (2018) Nature communications 9, 3489. PMID: 30154480
2. Schwarzbaum, PJ. et al. (2022) The Journal of biological chemistry 298, 101537. PMID: 35041824
3. Gulati, A. et al. (2025) Nature 643, 855-864. PMID: 40399679
Note For research use only
Images
  • Anti-Human SLC35B1 Recombinant Antibody (SAA2353)

    SDS-PAGE

    SDS-PAGE for Anti-Human SLC35B1 Antibody (SAA2353)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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