

| Каталожный номер | HC806014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SLC38A3 Polyclonal Antibody (HC806014) is a rabbit polyclonal antibody detecting SLC38A3. Suitable for Human.
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SLC38A3 (Lys234-Asn323). | ||||||||
| Цель | G17, N-system amino acid transporter 1, NAT1, Na(+)-coupled neutral amino acid transporter 3, SLC38A3, SN1, SNAT3, Sodium-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, System N amino acid transporter 1 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q99624 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Фон | Sodium-coupled neutral amino acid transporter 3 (SLC38A3) is a ~55 kDa protein. Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from astrocytes in the intercellular space for the replenishment of both neurotransmitters glutamate and gamma-aminobutyric acid (GABA) in neurons and also functions as the major influx transporter in ganglion cells mediating the uptake of glutamine. The transport activity is specific for L-glutamine, L-histidine and L-asparagine. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). The transport is pH dependent, saturable, Li(+) tolerant and functions in both direction depending on the concentration gradients of its substrates and cotransported ions. 1. Fei, YJ. et al. (2000) The Journal of biological chemistry 275, 23707-17. PMID: 10823827 | ||||||||
| Примечание | For research use only |
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