Anti-Human SLC4A7 Recombinant Antibody (SAA1974) (HA125013)

Name: Anti-Human SLC4A7 Recombinant Antibody (SAA1974)
Brand: abinScience
SKU: HA125013
Price: 110 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HA125013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

VHH-mFc

ID de clon

SAA1974

Objetivo

Electroneutral Na/HCO(3) cotransporter, Sodium bicarbonate cotransporter 3, NBC3, Sodium bicarbonate cotransporter 2, NBCn1, Solute carrier family 4 member 7, Bicarbonate transporter, SLC4A6, NBC2, SBC2, Sodium bicarbonate cotransporter 2b, NBC2B, BT, SLC4A7

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9Y6M7

RRID

Anti-Human SLC4A7 Antibody (SAA1974) (abinScience Cat# HA125013, RRID:AB_3727738)
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Forma

Liquid

Buffer de almacenamiento

30 mM Histidine, pH5.8, 10% sucrose, 0.02% Tween80

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Sodium bicarbonate cotransporter 3 (SLC4A7) is a ~136 kDa protein. Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Mediates the sodium-dependent bicarbonate transport important for pH recovery after acid load as well as for regulation of steady-state pH in the duodenum and vascular smooth muscle cells. Plays a key role in macrophage acidification, mediating bicarbonate import into the cytoplasm which is crucial for net acid extrusion and maintenance of cytoplasmic pH during phagocytosis. Provides cellular bicarbonate for de novo purine and pyrimidine synthesis and is a key mediator of de novo nucleotide synthesis downstream of mTORC1 signaling in proliferating cells.

1. Pushkin, A. et al. (1999) The Journal of biological chemistry 274, 16569-75. PMID: 10347222

2. Park, M. et al. (2002) The Journal of biological chemistry 277, 50503-9. PMID: 12403779

3. Loiselle, FB. et al. (2003) Molecular membrane biology 20, 307-17. PMID: 14578046

4. Loiselle, FB. et al. (2004) American journal of physiology. Cell physiology 286, C1423-33. PMID: 14736710

5. Sedlyarov, V. et al. (2018) Cell host & microbe 23, 766-774.e5. PMID: 29779931

6. Ali, ES. et al. (2022) Molecular cell 82, 3284-3298.e7. PMID: 35772404

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human SLC4A7 Antibody (SAA1974)

Referencias

Datasheet

Anti-Human SLC4A7 Recombinant Antibody (SAA1974).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo