Anti-Human SLC5A8 Recombinant Antibody (SAA0314) (HP275107)

Name: Anti-Human SLC5A8 Recombinant Antibody (SAA0314)
Brand: abinScience
SKU: HP275107
Price: 196 USD
Availability: InStock

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Даташит
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Обзор

Каталожный номер	HP275107
Реактивность видов	Human
Применения	ELISA, FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	VHH-mFC
ID клона	SAA0314
Цель	Apical iodide transporter, Sodium-coupled monocarboxylate transporter 1, SMCT1, AIT, Sodium iodide-related cotransporter, SMCT, Solute carrier family 5 member 8, Electrogenic sodium monocarboxylate cotransporter, SLC5A8
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q8N695
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.09% Sodium azide. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Sodium-coupled monocarboxylate transporter 1 (SLC5A8) is a ~66 kDa protein. Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. 1. Miyauchi, S. et al. (2004) The Journal of biological chemistry 279, 13293-6. PMID: 14966140 2. Coady, MJ. et al. (2004) The Journal of physiology 557, 719-31. PMID: 15090606 3. Itagaki, S. et al. (2006) Pharmaceutical research 23, 1209-16. PMID: 16729224 4. Martin, PM. et al. (2006) Journal of neurochemistry 98, 279-88. PMID: 16805814 5. Thangaraju, M. et al. (2006) Cancer research 66, 11560-4. PMID: 17178845 6. Gopal, E. et al. (2007) Pharmaceutical research 24, 575-84. PMID: 17245649 7. Coady, MJ. et al. (2007) Biophysical journal 93, 2325-31. PMID: 17526579 8. Miyauchi, S. et al. (2010) Biochimica et biophysica acta 1798, 1164-71. PMID: 20211600 9. Srivastava, S. et al. (2019) The journal of physiological sciences : JPS 69, 399-408. PMID: 30604288 10. Rodriguez, AM. et al. (2002) The Journal of clinical endocrinology and metabolism 87, 3500-3. PMID: 12107270
Примечание	For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human SLC5A8 Antibody (SAA0314)

Ссылки

Даташит

Anti-Human SLC5A8 Recombinant Antibody (SAA0314).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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