

| Número de catálogo | HA775014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human SLC6A19 Polyclonal Antibody (HA775014) is a rabbit polyclonal antibody detecting Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1; SLC6A19; B0AT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human SLC6A19 (Gly326-Ser413). | ||||||||
| Objetivo | Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1; SLC6A19; B0AT1 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q695T7 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Sodium-dependent neutral amino acid transporter B(0)AT1 (SLC6A19) is a ~71 kDa protein. Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity. 1. Kleta, R. et al. (2004) Nature genetics 36, 999-1002. PMID: 15286787 2. Seow, HF. et al. (2004) Nature genetics 36, 1003-7. PMID: 15286788 3. Kowalczuk, S. et al. (2008) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22, 2880-7. PMID: 18424768 4. Azmanov, DN. et al. (2008) Human mutation 29, 1217-21. PMID: 18484095 5. Camargo, SM. et al. (2009) Gastroenterology 136, 872-82. PMID: 19185582 6. Fairweather, SJ. et al. (2015) The Journal of biological chemistry 290, 24308-25. PMID: 26240152 | ||||||||
| Nota | For research use only |
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