中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HC031014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLC7A5 Polyclonal Antibody (HC031014) is a rabbit polyclonal antibody detecting Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter; SLC7A5; CD98LC; LAT1; MPE16 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC7A5 (Val148-Glu169&Gly215-Asn242&Thr298-Ser324&Lys479-Thr507). | ||||||||
| ターゲット | Large neutral amino acids transporter small subunit 1; 4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter; SLC7A5; CD98LC; LAT1; MPE16 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q01650 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Large neutral amino acids transporter small subunit 1 (SLC7A5) is a ~55 kDa protein. The heterodimer with SLC3A2 functions as a sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, leucine, histidine, methionine, tryptophan, valine, isoleucine and alanine. The heterodimer with SLC3A2 mediates the uptake of L-DOPA. Functions as an amino acid exchanger. May play a role in the transport of L-DOPA across the blood-brain barrier. May act as the major transporter of tyrosine in fibroblasts (Probable). 1. Prasad, PD. et al. (1999) Biochemical and biophysical research communications 255, 283-8. PMID: 10049700 2. Rossier, G. et al. (1999) The Journal of biological chemistry 274, 34948-54. PMID: 10574970 3. Yanagida, O. et al. (2001) Biochimica et biophysica acta 1514, 291-302. PMID: 11557028 4. Friesema, EC. et al. (2001) Endocrinology 142, 4339-48. PMID: 11564694 5. Simmons-Willis, TA. et al. (2002) The Biochemical journal 367, 239-46. PMID: 12117417 6. Kim, DK. et al. (2002) Biochimica et biophysica acta 1565, 112-21. PMID: 12225859 7. Li, S. et al. (2005) The Journal of biological chemistry 280, 20102-10. PMID: 15769744 8. Vumma, R. et al. (2008) Neuroscience letters 434, 56-60. PMID: 18262359 9. Milkereit, R. et al. (2015) Nature communications 6, 7250. PMID: 25998567 10. Yan, R. et al. (2019) Nature 568, 127-130. PMID: 30867591 | ||||||||
| 注意事項 | For research use only |
Lane 1: A549 cell lysate
Lane 2: Hela cell lysate
Lane 3: MCF-7 cell lysate
Lane 4: HepG2 cell lysate
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
