Anti-Human SLCO2A1 Polyclonal Antibody (HP622014)

Name: Anti-Human SLCO2A1 Polyclonal Antibody
Brand: abinScience
SKU: HP622014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HP622014

Description

Anti-Human SLCO2A1 Polyclonal Antibody (HP622014) is a rabbit polyclonal antibody detecting SLCO2A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SLCO2A1 (Met418-Ala518).

Cible

OATP2A1, Solute carrier family 21 member 2, Prostaglandin transporter, Solute carrier organic anion transporter family member 2A1, SLCO2A1, SLC21A2, PGT

Purification

Purified by antigen affinity column.

Numéro d'accès

Q92959

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Solute carrier organic anion transporter family member 2A1 (SLCO2A1) is a ~70 kDa protein. Mediates the transport of prostaglandins (PGs, mainly PGE2, PGE1, PGE3, PGF2alpha, PGD2, PGH2) and thromboxanes (thromboxane B2) across the cell membrane. PGs and thromboxanes play fundamental roles in diverse functions such as intraocular pressure, gastric acid secretion, renal salt and water transport, vascular tone, and fever. Plays a role in the clearance of PGs from the circulation through cellular uptake, which allows cytoplasmic oxidation and PG signal termination. PG uptake is dependent upon membrane potential and involves exchange of a monovalent anionic substrate (PGs exist physiologically as an anionic monovalent form) with a stoichiometry of 1:1 for divalent anions or of 1:2 for monovalent anions. Uses lactate, generated by glycolysis, as a counter-substrate to mediate PGE2 influx and efflux.

1. Chan, BS. et al. (2002) American journal of physiology. Renal physiology 282, F1097-102. PMID: 11997326

2. Gose, T. et al. (2016) Prostaglandins & other lipid mediators 122, 10-7. PMID: 26692285

3. Lu, R. et al. (1996) The Journal of clinical investigation 98, 1142-9. PMID: 8787677

4. Nomura, T. et al. (2004) Molecular pharmacology 65, 973-8. PMID: 15044627

5. Nakanishi, T. et al. (2017) The AAPS journal 20, 13. PMID: 29204966

6. Kang, J. et al. (2006) Human reproduction (Oxford, England) 21, 592-9. PMID: 16339169

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human SLCO2A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human SLCO2A1 Polyclonal Antibody (HP622014)

Aperçu

Images

Reférences

Fiche technique

SDS