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| カタログ番号 | HY298013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human SLPI Recombinant Antibody (SAA1833) (HY298013) is a mouse monoclonal antibody detecting SLPI in ELISA, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||
| アプリケーション | ELISA, WB | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1833 | ||||
| テスト済みアプリケーション | WB | ||||
| ターゲット | WFDC4, ALP, Antileukoproteinase, WAP four-disulfide core domain protein 4, SLPI, BLPI, Secretory leukocyte protease inhibitor, WAP4, Mucus proteinase inhibitor, HUSI-1, Seminal proteinase inhibitor, MPI, Protease inhibitor WAP4 | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P03973 | ||||
| RRID | Anti-Human SLPI Antibody (SAA1833) (abinScience Cat# HY298013, RRID:AB_3727596) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Antileukoproteinase (SLPI) is a ~14 kDa protein. Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. 1. Mulligan, MS. et al. (2000) The American journal of pathology 156, 1033-9. PMID: 10702419 2. Sallenave, JM. et al. (1991) Biological chemistry Hoppe-Seyler 372, 13-21. PMID: 2039600 3. Eisenberg, SP. et al. (1990) The Journal of biological chemistry 265, 7976-81. PMID: 2110563 4. Fukushima, K. et al. (2013) Journal of synchrotron radiation 20, 943-7. PMID: 24121345 5. Thompson, RC. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 6692-6. PMID: 3462719 6. Heinzel, R. et al. (1986) European journal of biochemistry 160, 61-7. PMID: 3533531 7. Klimenkova, O. et al. (2014) Blood 123, 1239-49. PMID: 24352879 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) |
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