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| カタログ番号 | HF704014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SLU7 Polyclonal Antibody (HF704014) is a rabbit polyclonal antibody detecting SLU7 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLU7 (Met28-Tyr173). | ||||||||
| ターゲット | Pre-mRNA-splicing factor SLU7, hSlu7, SLU7 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95391 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pre-mRNA-splicing factor SLU7 is a ~68 kDa protein. Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. 1. Chua, K. et al. (1999) Genes & development 13, 841-50. PMID: 10197984 2. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 3. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154 | ||||||||
| 注意事項 | For research use only. |
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