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Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257) (HW576013)

Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)
Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)
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Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHW576013
Reactividad de especiesHuman
AplicacionesELISA, IF, IP
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1
ID de clonSAA0257
Objetivo hBRM, SNF2A, Protein brahma homolog, SMARCA2, ATP-dependent helicase SMARCA2, SNF2-alpha, BRM, BAF190B, BRG1-associated factor 190B, Probable global transcription activator SNF2L2, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P51531
RRID Anti-Human SMARCA2 IP Antibody (SAA0257) (abinScience Cat# HW576013, RRID:AB_3729791)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) is a ~181 kDa protein. ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.

1. Liu, K. et al. (2004) Genes & development 18, 673-86. PMID: 15075294
2. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240
3. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204
Nota For research use only.
Imágenes
  • Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)

    SDS-PAGE

    SDS-PAGE for Anti-Human SMARCA2 IP Antibody (SAA0257)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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Working Solution
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