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Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257) (HW576013)

Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)
Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)
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  • 100ug
  • 1mg
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Aperçu
Numéro de catalogueHW576013
Reactivité des espècesHuman
ApplicationsELISA, IF, IP
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1
ID de cloneSAA0257
Cible hBRM, SNF2A, Protein brahma homolog, SMARCA2, ATP-dependent helicase SMARCA2, SNF2-alpha, BRM, BAF190B, BRG1-associated factor 190B, Probable global transcription activator SNF2L2, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P51531
RRID Anti-Human SMARCA2 IP Antibody (SAA0257) (abinScience Cat# HW576013, RRID:AB_3729791)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) is a ~181 kDa protein. ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.

1. Liu, K. et al. (2004) Genes & development 18, 673-86. PMID: 15075294
2. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240
3. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204
Note For research use only.
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  • Anti-Human SMARCA2 IP Recombinant Antibody (SAA0257)

    SDS-PAGE

    SDS-PAGE for Anti-Human SMARCA2 IP Antibody (SAA0257)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Recommandation

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