

| Каталожный номер | HW576013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA, IF, IP | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG1 | ||||
| ID клона | SAA0257 | ||||
| Цель | hBRM, SNF2A, Protein brahma homolog, SMARCA2, ATP-dependent helicase SMARCA2, SNF2-alpha, BRM, BAF190B, BRG1-associated factor 190B, Probable global transcription activator SNF2L2, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P51531 | ||||
| RRID | Anti-Human SMARCA2 IP Antibody (SAA0257) (abinScience Cat# HW576013, RRID:AB_3729791) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) is a ~181 kDa protein. ATPase involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. 1. Liu, K. et al. (2004) Genes & development 18, 673-86. PMID: 15075294 2. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240 3. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204 | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human SMARCA2 IP Antibody (SAA0257)



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