中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HP754014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SMARCC1 (Thr40-Asn277). | ||||||||
| ターゲット | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1, SWI/SNF complex subunit SMARCC1, BAF155, SMARCC1, BRG1-associated factor 155, SWI/SNF complex 155 kDa subunit | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q92922 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | SWI/SNF complex subunit SMARCC1 is a ~122 kDa protein. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. 1. Phelan, ML. et al. (1999) Molecular cell 3, 247-53. PMID: 10078207 2. Alpsoy, A. et al. (2018) The Journal of biological chemistry 293, 3892-3903. PMID: 29374058 | ||||||||
| 注意事項 | For research use only. |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
