Anti-Human SMARCD1 Polyclonal Antibody (HP029014)

Name: Anti-Human SMARCD1 Polyclonal Antibody
Brand: abinScience
SKU: HP029014
Price: 168 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug

Nombre :

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HP029014

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human SMARCD1 (Lys177-Ser410).

Cible

60 kDa BRG-1/Brm-associated factor subunit A, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, SWI/SNF complex 60 kDa subunit, BAF60A, SMARCD1, BRG1-associated factor 60A

Purification

Purified by antigen affinity column.

Numéro d'accès

Q96GM5

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) is a ~58 kDa protein. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.

1. Alpsoy, A. et al. (2018) The Journal of biological chemistry 293, 3892-3903. PMID: 29374058

2. Wang, W. et al. (1996) Genes & development 10, 2117-30. PMID: 8804307

3. Koszewski, NJ. et al. (2003) The Journal of steroid biochemistry and molecular biology 87, 223-31. PMID: 14698202

4. Hsiao, PW. et al. (2003) Molecular and cellular biology 23, 6210-20. PMID: 12917342

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human SMARCD1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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