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| カタログ番号 | HD667014 | ||||||||
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| 説明 |
Anti-Human SMPDL3B Polyclonal Antibody (HD667014) is a rabbit polyclonal antibody detecting SMPDL3B. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SMPDL3B (Gly21-Gly433). | ||||||||
| ターゲット | ASM-like phosphodiesterase 3b, ASML3B, ASMLPD, Acid sphingomyelinase-like phosphodiesterase 3b, EC:3.1.4.-, SMPDL3B | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q92485 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) is a ~50 kDa protein. Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling. Has in vitro phosphodiesterase activity, but the physiological substrate is unknown. Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro). 1. Heinz, LX. et al. (2015) Cell reports 11, 1919-28. PMID: 26095358 | ||||||||
| 注意事項 | For research use only |
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