

| Numéro de catalogue | HX240014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SNU13 Polyclonal Antibody (HX240014) is a rabbit polyclonal antibody detecting SNU13 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
||||||||
| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SNU13 (Met1-Val128). | ||||||||
| Cible | High mobility group-like nuclear protein 2 homolog 1, SNU13, U4/U6.U5 tri-snRNP 15.5 kDa protein, OTK27, hSNU13, SNU13 homolog, U4/U6.U5 small nuclear ribonucleoprotein SNU13, NHP2-like protein 1, NHP2L1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P55769 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||||||
| Informations d'utilisation du produit |
| ||||||||
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | NHP2-like protein 1 (SNU13) is a ~14 kDa protein. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. 1. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797 2. Bertram, K. et al. (2017) Cell 170, 701-713.e11. PMID: 28781166 3. Nottrott, S. et al. (1999) The EMBO journal 18, 6119-33. PMID: 10545122 4. Liu, S. et al. (2007) Science (New York, N.Y.) 316, 115-20. PMID: 17412961 5. Zhang, D. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2406961121. PMID: 39570315 | ||||||||
| Note | For research use only. |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
Accès rapide
Contactez-nous
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский