

| Каталожный номер | HC408014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SNW1 Polyclonal Antibody (HC408014) is a rabbit polyclonal antibody detecting SNW1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SNW1 (Ser14-Glu201). | ||||||||
| Цель | SNW1, SKIP, Ski-interacting protein, Nuclear receptor coactivator NCoA-62, SKIIP, Nuclear protein SkiP, SNW domain-containing protein 1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q13573 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | SNW domain-containing protein 1 (SNW1) is a ~61 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Required for the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. May recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770 | ||||||||
| Примечание | For research use only. |
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