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Anti-Human SNX2 Polyclonal Antibody (HT141014)

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Vista general
Número de catálogoHT141014
Descripción
Anti-Human SNX2 Polyclonal Antibody (HT141014) is a rabbit polyclonal antibody detecting SNX2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human SNX2 (Asp125-Ser277).
Objetivo Sorting nexin-2, Transformation-related gene 9 protein, TRG-9, SNX2, TRG9
Purificación Purified by antigen affinity column.
Número de acceso O60749
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Sorting nexin-2 (SNX2) is a ~58 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

1. Carlton, JG. et al. (2005) Journal of cell science 118, 4527-39. PMID: 16179610
2. Rojas, R. et al. (2007) Molecular and cellular biology 27, 1112-24. PMID: 17101778
3. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988
4. Lieu, ZZ. et al. (2010) European journal of cell biology 89, 379-93. PMID: 20138391
5. Prosser, DC. et al. (2010) Traffic (Copenhagen, Denmark) 11, 1347-62. PMID: 20604901
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SNX2 Polyclonal Antibody

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