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| カタログ番号 | HT336014 | ||||||||
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| 説明 |
Anti-Human SNX3 Polyclonal Antibody (HT336014) is a rabbit polyclonal antibody detecting SNX3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SNX3 (Met1-Ala162). | ||||||||
| ターゲット | SNX3, Protein SDP3, Sorting nexin-3 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O60493 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sorting nexin-3 (SNX3) is a ~18 kDa protein. Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Can also bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC/VPS). 1. Harterink, M. et al. (2011) Nature cell biology 13, 914-923. PMID: 21725319 2. Harrison, MS. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 267-72. PMID: 24344282 3. McGough, IJ. et al. (2018) Nature communications 9, 3737. PMID: 30213940 4. Chua, RY. et al. (2013) Immunology 139, 30-47. PMID: 23237080 | ||||||||
| 注意事項 | For research use only. |
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