Anti-Human SNX5 Polyclonal Antibody (HP226014)

Name: Anti-Human SNX5 Polyclonal Antibody
Brand: abinScience
SKU: HP226014
Price: 96 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HP226014

説明

Anti-Human SNX5 Polyclonal Antibody (HP226014) is a rabbit polyclonal antibody detecting SNX5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human SNX5 (Met1-Asp171).

ターゲット

SNX5, Sorting nexin-5

精製

Purified by antigen affinity column.

アクセッション番号

Q9Y5X3

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Sorting nexin-5 (SNX5) is a ~46 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

1. Merino-Trigo, A. et al. (2004) Journal of cell science 117, 6413-24. PMID: 15561769

2. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988

3. Wassmer, T. et al. (2007) Journal of cell science 120, 45-54. PMID: 17148574

4. Hara, S. et al. (2008) Molecular biology of the cell 19, 3823-35. PMID: 18596235

5. Sun, Y. et al. (2013) Developmental cell 25, 144-55. PMID: 23602387

6. Schill, NJ. et al. (2014) Journal of cell science 127, 2189-203. PMID: 24610942

7. Lim, JP. et al. (2008) BMC cell biology 9, 58. PMID: 18854019

8. Wang, JT. et al. (2010) PloS one 5, e13763. PMID: 21048941

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human SNX5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human SNX5 Polyclonal Antibody (HP226014)

概要

イメージ

参考文献

データシート

SDS