

| Каталожный номер | HP226014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SNX5 Polyclonal Antibody (HP226014) is a rabbit polyclonal antibody detecting SNX5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SNX5 (Met1-Asp171). | ||||||||
| Цель | SNX5, Sorting nexin-5 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9Y5X3 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Sorting nexin-5 (SNX5) is a ~46 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). 1. Merino-Trigo, A. et al. (2004) Journal of cell science 117, 6413-24. PMID: 15561769 2. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988 3. Wassmer, T. et al. (2007) Journal of cell science 120, 45-54. PMID: 17148574 4. Hara, S. et al. (2008) Molecular biology of the cell 19, 3823-35. PMID: 18596235 5. Sun, Y. et al. (2013) Developmental cell 25, 144-55. PMID: 23602387 6. Schill, NJ. et al. (2014) Journal of cell science 127, 2189-203. PMID: 24610942 7. Lim, JP. et al. (2008) BMC cell biology 9, 58. PMID: 18854019 8. Wang, JT. et al. (2010) PloS one 5, e13763. PMID: 21048941 | ||||||||
| Примечание | For research use only. |
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