

| Número de catálogo | HD615014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human SOX11 Polyclonal Antibody (HD615014) is a rabbit polyclonal antibody detecting SOX11. Suitable for Rat, Mouse, and Human.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human SOX11 (Asn54-Tyr113). | ||||||||
| Objetivo | SOX11, Transcription factor SOX-11 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P35716 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Transcription factor SOX-11 (SOX11) is a ~46 kDa protein. Transcription factor that acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron. Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. 1. Tsurusaki, Y. et al. (2014) Nature communications 5, 4011. PMID: 24886874 2. Hempel, A. et al. (2016) Journal of medical genetics 53, 152-62. PMID: 26543203 | ||||||||
| Nota | For research use only |
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