

| Numéro de catalogue | HF883014 | ||||||||
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| Description |
Anti-Human SOX30 Polyclonal Antibody (HF883014) is a rabbit polyclonal antibody detecting SOX30 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SOX30 (Thr292-Gly403). | ||||||||
| Cible | Transcription factor SOX-30, SOX30 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O94993 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Transcription factor SOX-30 (SOX30) is a ~81 kDa protein. Acts both as a transcriptional activator and a repressor. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif. Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling. 1. Osaki, E. et al. (1999) Nucleic acids research 27, 2503-10. PMID: 10359848 2. Han, F. et al. (2018) EBioMedicine 31, 253-266. PMID: 29739711 | ||||||||
| Note | For research use only. |
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